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Depression: Antidepressants or other medications

A forum to discuss antidepressants for prostate cancer-related depression - commonly triggered by diagnosis and treatment side effects. What has been your experience with anti-depressants? Do you have any tips to share?

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  1. I am currently using paxil. No big changes yet after 2 weeks

    1. Thanks for commenting, . I have some friends who found that it takes a while for their mood to start responding to these medications, but I hope your doc will help you figure out whether it's the right option or not. Is this the first one you've tried? I've heard it can take a few tries of different meds to find the right fit. Really glad you're looking for solutions! - Nina, ProstateCancer.net Team

  2. Life long treatment of a lupron injection every 3-5 months, hot flashes, mood swings, depression. Take venlafaxine twice a day...not much help.

    1. I also get a Lupron shot once every three months (for life) and I get most of the same side effects as everyone else. What has worked for me is Wellbutrin. Due to peripheral neuropathy from chemo, I switched my fluoxetine (Prozac) to duloxetine (Cymbalt) and that’s to be a good combo. I still have small bouts of depression, but it’s really been under control. I’m two years out (stage 4) and I definitely felt better overall the second year. We’ll see what year three brings. – Doug, ProstateCancer.net Team

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