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TRUS

I'm scheduled for a TRUS next Friday but am concerned that I not only don't know enough about the biopsy procedure, but I'm concerned also that the difference of opinions and lack of documentation of the new determination about my MRI between radiologists and urologists, that something will be missed. Please chime in if you had a TRUS, and any problems associated with it? Should I seek another MRI. My daughter who is 20 wants me to get the biopsy right away, but I'm the type of person that has to know that its the right thing to do. My PSA has been elevated since Nov, 2021 12 months, on my initial trip to MDanderson, it remained the same slightly lower but still at 5.16. I feel I have time to seek another specialist, if you see my previous discussions you will see the issue with the MRI, and what radiologists have said. Thoughts on the TRUS and if you have had a similar experience?
thank you

  1. I assume by TRUS you mean a TRUS guided biopsy. You are right in preferring imaging to an actual biopsy and it is the current and sensible practice to scan first to establish the need for a biopsy. One day, a biopsy may not even be required to establish the presence or absence of a carcinoma in the prostate.


    You have not clarified whether you have got a mpMRI done and, if so, what the report indicates. For instance, if the mpMRI did not find evidence of a lesion in the prostate, you could discuss with your doctor if a PSMA-PET scan could be first done for detecting the presence of a lesion and then resort to a biopsy based on the report.

    1. Yep, in my previous posts, I mentioned I had an 3tMRI which was initially a PIrads 4, but then Checked with 2 radiologists from Houston, and they said there was an additional lesion and the one that MD Anderson confirmed they weren't worried about it, so they asked me to contact the Anderson Dr and give them the locations, and after the clinical team w/4 radiologists reviewed it again they said there was 2 areas identified that were either a shaded area on both sides which is a common pitfall for radiologists or it was suspicious. Downgraded to PIrads3. The biopsy was postponed by me and now I have one other Dr. taking a look at the images and getting a third look. Based on the link the Dr from MDA sent in my chart, it almost sounds like this area is of minimal concern to the trained eye, its a commonly mistaken area for cancer, due to location and shading of the area.

  2. I replied in the other topic started by you. Even a clear PSMA-PET scan or mpMRI finding of a lesion would probably carry the advice of “clinical correlation”. Makes a lot of sense to be sure whether an invasive biopsy is required at all.

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