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Bike Riding with Prostate Cancer

I have a question about bike riding and what might happen to my PSA scores because of it. Before my diagnosis I was always told to refrain from bike riding for a week or so prior to my annual physical to make sure my PSA readings were true.

I was diagnosed almost exact a year ago with a Gleason score of 4+3 and a PSA which peaked at 97 in January of 2024 when I underwent an orchiectomy; since then I've started taking a daily Erleada dose and now have a PSA reading <0.1. Given my cancer has metastasized my doctors recommended radiation treatments in lieu of having my prostate removed, and as luck would have it, my radiation treatments are only two miles from my home, so, weather and meeting schedules permitting, I am riding my bike to and from my appointments.

And now finally to my question; is it likely my PSA will (temporarily) go back up from the bike riding, or given all the other changes in my body over the last year, cycling is no longer an issue when it comes to PSA levels?

  1. What I found is "On average, cycling can increase PSA levels by 9.5% in healthy male cyclists over 50 years old" and cycling is not advised within 24-48 hours of a PSA test. An ~10% increase is not that much. Say a 5 to a 5.5 or a 2 to a 2.2. It's not like your PSA goes from 2 to 20

    1. Interesting; my experience with running was much more significant. A few years ago I forgot about an upcoming blood test and ran 42 miles in the 72 hours prior to the test; my PSA was over 9; when I had it retested a week later it was 1.4.

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