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Comparison between brachytherapy (SEED implant) and Cyberknife (SBRT)?

59yr, Gleason 4+3=7, PSA7.8, T2c.

Looking for radiation treatment in form of SBRT (Cyberknife) and Brachytherapy. Where can I find the best comparison between the two methods to ultimately decide which would be best for my case?

It seems statistically brachytherapy has best long term outcomes (lower rate of recurrence) and has been around for a long time. However, Cyberknife apparently is close in efficacy to brachy, but it hasn't been around as long to judge 15 year intervals.

Maybe there are some other moments I have to pay attention to?

  1. Hi . It seem you are correct that you are not going to find results going that far back for Cyberknife for prostate cancer (although it has been used for other treatments, such as brain cancer for longer). I did find this article comparing Cyberknife to brachytherapy in two studies and finding that "These studies confirm that SBRT, completed in either four or five treatment visits results in similar favorable outcomes:" https://pcri.org/insights-blog/2017/10/3/our-journey-to-establish-prostate-sbrt-as-a-standard-of-care. Of course, each case is different and there may be specific reasons doctors feel a particular treatment is more suited to a particular patient. Best, Richard (ProstateCancer.net Team)

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