Managing Lupron's Sexual Side Effects

There has been considerable interest in the ProstateCancer.net community about the sexual side effects of medications and treatments, and the issues they’ve caused for many people.

The one name that seems to appear over and over again is the hormone therapy Lupron. This prescribed treatment for prostate cancer may be good at what it does. However, it can have a serious impact on the quality of life for some.

What are the side effects of Lupron?

Some of the most common potential side effects can include:¹

• Hot flashes
• Fatigue
• Gastrointestinal issues
• Pain
• Testicle shrinkage
• Sexual side effects like impotence

So, let's take a look at Lupron. What does it do, and are there any possible solutions to the sexual side effects?

How does Lupron work?

Lupron is used to treat advanced prostate cancer and given via injection. Simply, it tells the body to stop creating sex hormones. In men, this decreases the level of testosterone to "starve" prostate cancer. (But with that said, testosterone levels can actually rise in the first few weeks of receiving Lupron.)¹

Changes to quality of life on treatment

Here, I would like to make two quick points. First, I’d like to mention the general quality of life for those who are taking Lupron. If you are not having any side effects and your treatment is working, that is excellent news.

If you are suffering from side effects, how is your overall quality of life? While the medication is doing its job, is it making your life miserable? From what I have read about Lupron from some people on this site, something may feel off. Yes, this medication is saving their lives, but at what cost?

How to discuss sexual side effects with your doctor

If your doctor says they are going to prescribe Lupron as your treatment, ask them questions. Most drugs come with the fold-out sheet that explains all the side effects. But they may be written in a small font that is hard to read and comprehend.

Ask your doctor about the major side effects and what the drug will do to various aspects of your life. For example, how it could affect your sex life. This way, you can make an informed decision.

Also ask how long you will have to be on the treatment. I believe an educated patient is a happier patient. While I am not telling you to second-guess their treatment decision, it is fair to ask for an alternative or other option.

The impact of sexual side effects

Removing a piece of your sexuality can have major mental and physical repercussions, including an effect on your relationships. From reading the comments here, too many times a lover has not wanted to stay with “a man who cannot perform” sexually. Treating cancer is one thing. Losing a marriage/relationship is another.

Be sure to talk to your doctor to get the answers you need.