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Active surveillance or not ?

I’ve been diagnosed with a 3+4 prostate cancer, cancer present in 8/12 cores, only 10% grade 4 cells and my PSA Is persistently under 10 (last was at 8.2). No metastasis, no symptoms. My oncologist seems to prefer radiotherapy, but suggested active surveillance as an option. I’m 65, I presently have a very good quality of life including a very healthy sex life. I’m thinking active surveillance until the next control (MRi, biopsy, PSA DRE) and if my situation worsenes, then go for treatment. Suck on the fence, what would you do ?

  1. Hi . I can't personally speak to this situation. I do know that there are a lot of factors that go into whether active surveillance is an option for an individual case and even then the person must choose what is best for them. A Gleason 3+4 can present the option of active surveillance and your doctor seems to think it could be for you. Did you have a Prolaris test done? This test can give an assessment of the risk of prostate cancer progression (see: https://bjui-journals.onlinelibrary.wiley.com/doi/10.1111/bju.14452). Hopefully others will chime in with their experience. Please feel free to keep us posted on how you are doing and to ask additional questions. Best, Richard (ProstateCancer.net Team)

    1. I’m in a very similar situation as you and am going to stay on active surveillance as long as I can. Going for 1 year follow up mri and then targeted biopsy to make sure things are the same as they were a year ago

      1. -Look up micromets. They were once thought of as a late stage thing. But they now realize mets are thrown off much earler. Early mets are weak, later mets are strong due to DNA morphing.
        -look up DNA and tumors. They have sampled various parts of a tumor and find all different DNA. Cancer is always adapting if you give it time.

        1. similar situation, diagnosed 1 week ago 3+4 with 40% pattern 4, PSA 6. I have already scheduled for a Davinci in June. See Dr. Scholz on youtube. he says max. 5% pattern 4 for AS

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