Hate to say this but you just do not know how hormone shots (ADT will impact you until you are on them . Been there when I was on Lupron ... and for me it was difficult with hot flashes, significant weight gain and emotional swings. Most men react in some way to the shots but to what level is hard to know in advance. I have several guys in my group who say it was not bad and others who are not very happy with the impact. I wish there was a more definitive answer - Where are you on your journey? Dennis(ProstatCancer.net TEAM)