caret icon Back to all discussions

Likelihood of metastasis to bone?

I'm a 66 year-old generally healthy male. My PSA has gone from 1.5 to 2.5 over the past three years. My father had PCa. I tend to get anxiety over health issues and pushed my doctor to get a prostate MRI. I had the MRI last October and it showed two lesions - a PIRADS 2 and a PIRADS 3. I also had the ExoDx urine test and it came back with a 23. Based on all of this, I'm scheduled for a biopsy in a few weeks.

The reason for my post is that I noticed some tenderness/pain in the top middle of my thigh last week. This is most likely unrelated to the prostate issue, but I'm paranoid that it could be metastasis to the femur. My MRI didn't show any issues with lymph node or pelvic/lumbar areas. From what I've read, it would be unlikely to be in the femur without also being in the pelvic/lumbar which were clear in the MRI. It would also be unlikely to be in the bone with a PSA of only 2.5. Am I being overly paranoid? Thanks in advance.

  1. Hi I can understand why you would be anxious, it must be hard to not immediately be concerned about every ache and pain. I am glad to hear you have a biopsy soon and that you were an advocate for yourself. I am sending you over an article with more information about this plus various testing options, I hope this is helpful: https://prostatecancer.net/diagnosis/test-spread. Please keep us posted on how you are doing. Jill, prostatecancer.net team

    1. “From what I've read, it would be unlikely to be in the femur without also being in the pelvic/lumbar which were clear in the MRI. It would also be unlikely to be in the bone with a PSA of only 2.5. “
      I agree with you. Lol


      Even though you may have PCa, with a low PSA, tumors are also smaller. The industry has great difficulty imaging small things.


      I was given the option to have a saturation biopsy vs std 12 pin. I took the saturation biopsy and they found the cancer. I really didn’t want to keep rerunning this movie over and over spanning ... a long time.


      Sounds like you are nice and early. I think the industry also has difficulty with “early”. Everything they do is late. A little or alot late. Be prepared.

      1. Here is a good website to compare odds of cure for the major treatment paths. You have to determine your stage, low risk, intermediate, or high risk (risk of recurrence). So if you are intermediate, pull up the intermediate chart and you can see the odds of 10-20 yr survival, etc. based on the treatment you pick.

        https://www.prostatecancerfree.org/compare-prostate-cancer-treatments/

        It is best viewed on computer or just print it on paper. Not so viewable on phone.

        To make the graphs easier to read, i drew a dot on the endpoints of the elipses, and then drew a line through the dots. This turns the elipses into lines.

        Also be aware the the graphs don’t show any salvage radiation benefit. This would boost the surgery odds up a bit.

        Also beware, this is a very dysfunctional industry from my view. Loads of bad info mixed in with the good info. Same with the docs. Some of them are more dangerous than the cancer.

        1. It is easy to let the imagination run wild when facing a prostate cancer diagnosis . Having faced and beaten PCa 3 times I fully agree with that it is easy to suspect that every ache is related to cancer. When I was told i had a spot of PCa on my hip bone following a PMSA Pet scan I was convinced I knew where it . YUP I was totally wrong.


          It is not easy but as best you can let the professionals give you advice and then verify . By the way the spot on the bone has been successfully treated as i caught it early after my post op PSA went from 0.02 to 0.38 Dennis (ProstateCancer.net TEAM)

          Please read our rules before posting.