I had my first biopsy in July 2017 - results were 3+3. MRI was Pirads 2. PSA was 5. Since then I have had 3 additional biopsies/MRIs. My second biopsy was clean, next two 3+3. All MRIs Pirads 2. PSA has ranged between 5, down to 3.5 and up to 5.2 during these close to 8 years. Going for my 5th biopsy next month which will be 33 months after my last one. My guess is if my second biopsy (clean) was my first I would have never had a second biopsy based on my PSA staying steady. Is there ever a point where if the biopsy does not change from 3+3 that they eliminate them? Doesn't this many biopsies do damage to the prostate? Tough getting a straight answer from my urologist on this.