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Just got the bad news/good news

59 years old. Annual PSA over the last several years was creeping up very slowly. Latest test in Nov 2022, it jumped from 2.4 to 3.2. Went back 6 weeks later and it was 3.4. Primary care doctor felt a nodule on left side during DRE. Sent me to a urologist who was concerned between jump in PSA and nodule. Had biopsy done two weeks ago. Urologist said 4 out of 12 cores showed positive for cancer. Lab report I read online said 15 cores were taken so I need to clarify. All positives were on left side in location of nodule. Said there was some perineurial invasion but my Gleason score was a 3+3=6, so that's the good news. My urologist wants me to have my prostate removed. I'm not so sure. I've been doing a TON of research and talking to friends and co workers that have dealt with prostate cancer. I currently have an appt with my primary care doctor and am expecting a call from a local oncologist, for an appt. I would like to push for additional testing. Perhaps an MRI, Pet Scan, Bone scan and am interested in the Prolaris genomic testing. I figure, the more testes, the better overall picture I will have. Once I have all of that information, I'm going to get a referral and go up to Dana Farber for another opinion. I'm lucky to live an hour away from some of the best hospitals in the country. I'm hoping I can get away with active surveillance for at least 18 months as I'm set to retire then. If I need surgery or treatment down the line, it'll be easier in retirement.

  1. @Brsox, Thanks for sharing so much of your journey with us. I thought I was reading my father's story for a minute. It looks like you have a great team of doctors. That is good. My father had the surgery when he was 72, worked until he was 82, and just had his 90th birthday. You do what's best for you. We are here if you need us. Let us know what you find out in your 2nd opinion. Diane (Team Member)

    1. @Brsox, Having a 3+3=6 is indeed the good news part of what you have learned. I was 62 when my PSA rose above 5.0 triggering a biopsy, one of the biopsy cores came in at a Gleason 9, and several at Gleason 8. With those scores my care team automatically scheduled me for an MRI and Bone scan (both came back negative). After lots of research and numerous 2nd opinions, I chose robotic surgery by a very experienced (and respected) surgeon and researcher. He also sent my post surgery tissue out for Decipher genetic testing. I believe they are now able to run the genetic testing on biopsy cores to help guide the treatment decision(s). Please keep us posted as their is a lot of personal experiences and compassion on this web site.

      1. Brsox,
        I'm 58 and have a similar journey that I have posted in this forum. PSA above 4, Gleason 3+3=6 in 4 of 12 cores, nodule. Long and short of it was I choose to do robotic proctectomy 5 months post my Biopsy on 4/6/23. My advice is everyone situation is different but what is common is get all the information you can before making your decision and get a second opinion on the information from the top medical instituations that specialize in prostate cancer (all treatments). Why sugery for me 5 things. 1.) Had decipher testing on my biopsy samples and came back high risk, 2) Family history of death due to prostate cancer. 3.) If you have prostate cancer confined to prostate (which I had ) really positive odds if you have it removed will not be dealing with it in the future ... 4) Procedure allows for excellent results not only of elimination of cancer but also preserving Continence and ED side effects. 5.) Ability to know exactly what I was dealing with once they removed my prostate and did pathology on it... Was upgrade from grade group 1 (gleason 6 to group 2 gleason 7) .....


        Again everyone situation is different and their are many factors to consider. You are going about it the right way... educate get all the right info and make decision that is right for you. Wish you the best and let me know if you have questions...



        1. Thanks for all of the advice. I have an appt on June 7th at Brigham and Women's in Boston with one of the top doctors in the field. He is chief of Urology at Brigham and Women's, did his fellowship at Johns Hopkins, and is a professor of surgery at Harvard Medical School. He has written or co written many articles on prostate cancer. He also performed robotic, nerve sparing prostate surgery on two co workers and they all had excellent results. I'm hoping to have Decipher testing and an MRI to confirm my Gleason 6 score. Then I will make a decision between surgery now or active surveillance for a while.

          1. Hi . Really sounds like you have a plan lined up. It really was good news that the biopsy came back Gleason 6 because it affords you the luxury of time to get the information, the second opinion, and make an informed decision best for you. Please feel free to keep us posted on how things go. Wishing you the best. Richard (ProstateCancer.net Team)

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