I was dx’d last October with stage 4 prostate cancer. My initial PSA was 5,306. I started chemo (standard six cycles of docetaxel) and Lupron (ADT/hormone therapy) simultaneously. My PSA has down considerably with each six week checkup. Last month I was at 22.09. This week if went up to 24.49. After nine months this was the first time it’s gone up. Granted not by much and nowhere near the drastic amount it’s come down each checkup in the past. At the moment I’m not too worried. One (clinically insignificant) result, not a trend. Be curious how much variance other people have in their PSA.